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Development of Highly Selective Pyrimidine-Based Aldosterone Synthase (CYP11B2) Inhibitors
[Image: see text] Excess aldosterone production and signaling are primary contributors to numerous cardiovascular disorders including primary aldosteronism and resistant hypertension. Recently, inhibition of aldosterone synthesis via the enzyme aldosterone synthase (CYP11B2) has been pursued to amel...
में बचाया:
| में प्रकाशित: | ACS Med Chem Lett |
|---|---|
| मुख्य लेखकों: | , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Chemical
Society
2019
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| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6628572/ https://ncbi.nlm.nih.gov/pubmed/31312408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00152 |
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