The activin receptor is stimulated in the skeleton, vasculature, heart and kidney during chronic kidney disease.

We examined activin receptor type IIA (ActRIIA) activation in chronic kidney disease (CKD) by signal analysis and inhibition in mice with Alport syndrome, using the ActRIIA ligand trap RAP-011 initiated in 75 day old Alport mice. At 200 days of age there was severe CKD and associated Mineral and Bon...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Kidney Int
Egile Nagusiak: Williams, Matthew J., Sugatani, Toshifumi, Agapova, Olga A., Fang, Yifu, Gaut, Joseph P., Faugere, Marie-Claude, Malluche, Hartmut H., Hruska, Keith A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628245/
https://ncbi.nlm.nih.gov/pubmed/28843411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.06.016
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