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Class I-Histone Deacetylase (HDAC) Inhibition is Superior to pan-HDAC Inhibition in Modulating Cisplatin Potency in High Grade Serous Ovarian Cancer Cell Lines

High grade serous ovarian cancer (HGSOC) is the most common and aggressive ovarian cancer subtype with the worst clinical outcome due to intrinsic or acquired drug resistance. Standard treatment involves platinum compounds. Cancer development and chemoresistance is often associated with an increase...

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Pubblicato in:Int J Mol Sci
Autori principali: Bandolik, Jan J., Hamacher, Alexandra, Schrenk, Christian, Weishaupt, Robin, Kassack, Matthias U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627993/
https://ncbi.nlm.nih.gov/pubmed/31234549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20123052
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