Načítá se...

Activation of LXR Receptors and Inhibition of TRAP1 Causes Synthetic Lethality in Solid Tumors

Cholesterol is a pivotal factor for cancer cells to entertain their relentless growth. In this case, we provide a novel strategy to inhibit tumor growth by simultaneous activation of liver-X-receptors and interference with Tumor Necrosis Factor Receptor-associated Protein 1 (TRAP1). Informed by a tr...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cancers (Basel)
Hlavní autoři: Nguyen, Trang Thi Thu, Ishida, Chiaki Tsuge, Shang, Enyuan, Shu, Chang, Bianchetti, Elena, Karpel-Massler, Georg, Siegelin, Markus D.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627953/
https://ncbi.nlm.nih.gov/pubmed/31181660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11060788
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!