Identification of Plasmodium falciparum Mitochondrial Malate: Quinone Oxidoreductase Inhibitors from the Pathogen Box

Malaria is one of the three major global health threats. Drug development for malaria, especially for its most dangerous form caused by Plasmodium falciparum, remains an urgent task due to the emerging drug-resistant parasites. Exploration of novel antimalarial drug targets identified a trifunctiona...

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Veröffentlicht in:Genes (Basel)
Hauptverfasser: Wang, Xinying, Miyazaki, Yukiko, Inaoka, Daniel Ken, Hartuti, Endah Dwi, Watanabe, Yoh-Ichi, Shiba, Tomoo, Harada, Shigeharu, Saimoto, Hiroyuki, Burrows, Jeremy Nicholas, Benito, Francisco Javier Gamo, Nozaki, Tomoyoshi, Kita, Kiyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627850/
https://ncbi.nlm.nih.gov/pubmed/31234346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10060471
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