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RNF34 functions in immunity and selective mitophagy by targeting MAVS for autophagic degradation

Viral infection triggers the formation of mitochondrial antiviral signaling protein (MAVS) aggregates, which potently promote immune signaling. Autophagy plays an important role in controlling MAVS‐mediated antiviral signaling; however, the exact molecular mechanism underlying the targeted autophagi...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: He, Xiang, Zhu, Yongjie, Zhang, Yanhong, Geng, Yunqi, Gong, Jing, Geng, Jin, Zhang, Pingping, Zhang, Xiaotong, Liu, Ning, Peng, Yumeng, Wang, Chenbin, Wang, Yujie, Liu, Xin, Wan, Luming, Gong, Feng, Wei, Congwen, Zhong, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627233/
https://ncbi.nlm.nih.gov/pubmed/31304625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100978
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