Identification of Tyrosine-9 of MAVS as Critical Target for Inducible Phosphorylation That Determines Activation

BACKGROUND: Innate immunity to viruses involves receptors such as RIG-I, which senses viral RNA and triggers an IFN-β signaling pathway involving the outer mitochondrial membrane protein MAVS. However, the functional status of MAVS phosphorylation remains elusive. METHODOLOGY/PRINCIPAL FINDINGS: Her...

Full description

Saved in:
Bibliographic Details
Main Authors: Wen, Chaoyang, Yan, Zhifeng, Yang, Xiaoli, Guan, Kai, Xu, Changzhi, Song, Ting, Zheng, Zirui, Wang, Wenjun, Wang, Ying, Zhao, Man, Zhang, Yanhong, Xu, Tao, Dou, Jianping, Liu, Jingmei, Xu, Quanbin, He, Xiang, Wei, Congwen, Zhong, Hui
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406013/
https://ncbi.nlm.nih.gov/pubmed/22844514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041687
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items