Identification of Tyrosine-9 of MAVS as Critical Target for Inducible Phosphorylation That Determines Activation

BACKGROUND: Innate immunity to viruses involves receptors such as RIG-I, which senses viral RNA and triggers an IFN-β signaling pathway involving the outer mitochondrial membrane protein MAVS. However, the functional status of MAVS phosphorylation remains elusive. METHODOLOGY/PRINCIPAL FINDINGS: Her...

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מידע ביבליוגרפי
Main Authors: Wen, Chaoyang, Yan, Zhifeng, Yang, Xiaoli, Guan, Kai, Xu, Changzhi, Song, Ting, Zheng, Zirui, Wang, Wenjun, Wang, Ying, Zhao, Man, Zhang, Yanhong, Xu, Tao, Dou, Jianping, Liu, Jingmei, Xu, Quanbin, He, Xiang, Wei, Congwen, Zhong, Hui
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406013/
https://ncbi.nlm.nih.gov/pubmed/22844514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041687
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