Molecular Comparison of Imatinib-Naïve and Resistant Gastrointestinal Stromal Tumors: Differentially Expressed microRNAs and mRNAs

Despite the success of imatinib in advanced gastrointestinal stromal tumor (GIST) patients, 50% of the patients experience resistance within two years of treatment underscoring the need to get better insight into the mechanisms conferring imatinib resistance. Here the microRNA and mRNA expression pr...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Amirnasr, Azadeh, Gits, Caroline M.M., van Kuijk, Patricia F., Smid, Marcel, Vriends, Anne L.M., Rutkowski, Piotr, Sciot, Raf, Schöffski, Patrick, Debiec-Rychter, Maria, Sleijfer, Stefan, Wiemer, Erik A. C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627192/
https://ncbi.nlm.nih.gov/pubmed/31238586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11060882
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