Deregulated microRNAs in neurofibromatosis type 1 derived malignant peripheral nerve sheath tumors

Malignant peripheral nerve sheath tumors (MPNST) are aggressive cancers that occur spontaneously (sporadic MPNST) or from benign plexiform neurofibromas in neurofibromatosis type 1 (NF1) patients. MPNSTs metastasize easily, are therapy resistant and are frequently fatal. The molecular changes underl...

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Publicado no:Sci Rep
Main Authors: Amirnasr, Azadeh, Verdijk, Robert M., van Kuijk, Patricia F., Kartal, Pinar, Vriends, Anne L. M., French, Pim J., van Royen, Martin E., Taal, Walter, Sleijfer, Stefan, Wiemer, Erik A. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031337/
https://ncbi.nlm.nih.gov/pubmed/32076030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59789-4
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