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Melanoma Progression Inhibits Pluripotency and Differentiation of Melanoma-Derived iPSCs Produces Cells with Neural-like Mixed Dysplastic Phenotype

Melanomas are known to exhibit phenotypic plasticity. However, the role cellular plasticity plays in melanoma tumor progression and drug resistance is not fully understood. Here, we used reprogramming of melanocytes and melanoma cells to induced pluripotent stem cell (iPSCs) to investigate the relat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Stem Cell Reports
Päätekijät: Castro-Pérez, Edgardo, Rodríguez, Carlos I., Mikheil, Dareen, Siddique, Shakir, McCarthy, Alexandra, Newton, Michael A., Setaluri, Vijayasaradhi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627006/
https://ncbi.nlm.nih.gov/pubmed/31231022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.05.018
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