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Notch Signaling Activation Induces Cell Death in MAPKi-resistant Melanoma Cells
The role of Notch signaling in melanoma drug resistance is not well understood. In this study, we show that although NOTCH proteins are upregulated in metastatic melanoma cell lines, Notch signaling inhibition had no effect on cell survival, growth, migration or the sensitivity of BRAFV600E-melanoma...
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| Publicado no: | Pigment Cell Melanoma Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6581614/ https://ncbi.nlm.nih.gov/pubmed/30614626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12764 |
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