Melanoma Progression Inhibits Pluripotency and Differentiation of Melanoma-Derived iPSCs Produces Cells with Neural-like Mixed Dysplastic Phenotype

Melanomas are known to exhibit phenotypic plasticity. However, the role cellular plasticity plays in melanoma tumor progression and drug resistance is not fully understood. Here, we used reprogramming of melanocytes and melanoma cells to induced pluripotent stem cell (iPSCs) to investigate the relat...

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Gepubliceerd in:Stem Cell Reports
Hoofdauteurs: Castro-Pérez, Edgardo, Rodríguez, Carlos I., Mikheil, Dareen, Siddique, Shakir, McCarthy, Alexandra, Newton, Michael A., Setaluri, Vijayasaradhi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627006/
https://ncbi.nlm.nih.gov/pubmed/31231022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.05.018
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