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Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids
Mutations in the gene encoding the type II transmembrane protease 3 (TMPRSS3) cause human hearing loss, although the underlying mechanisms that result in TMPRSS3-related hearing loss are still unclear. We combined the use of stem cell-derived inner ear organoids with single-cell RNA sequencing to in...
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| Publicado no: | Stem Cell Reports |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6626982/ https://ncbi.nlm.nih.gov/pubmed/31204303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.05.014 |
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