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PKM2 coordinates glycolysis with mitochondrial fusion and oxidative phosphorylation
A change in the metabolic flux of glucose from mitochondrial oxidative phosphorylation (OXPHOS) to aerobic glycolysis is regarded as one hallmark of cancer. However, the mechanisms underlying the metabolic switch between aerobic glycolysis and OXPHOS are unclear. Here we show that the M2 isoform of...
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| Publicado no: | Protein Cell |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Higher Education Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6626593/ https://ncbi.nlm.nih.gov/pubmed/30887444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-019-0618-z |
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