Trpm2 enhances physiological bioenergetics and protects against pathological oxidative cardiac injury: Role of Pyk2 phosphorylation

The mechanisms by which Trpm2 channels enhance mitochondrial bioenergetics and protect against oxidative stress induced cardiac injury remain unclear. Here, the role of proline-rich tyrosine kinase 2 (Pyk2) in Trpm2 signaling is explored. Activation of Trpm2 in adult myocytes with H(2)O(2) resulted...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Cell Physiol
Main Authors: Miller, Barbara A., Wang, JuFang, Song, Jianliang, Zhang, Xue-Qian, Hirschler-Laszkiewicz, Iwona, Shanmughapriya, Santhanam, Tomar, Dhanendra, Rajan, Sudasan, Feldman, Arthur M., Madesh, Muniswamy, Sheu, Shey-Shing, Cheung, Joseph Y.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626587/
https://ncbi.nlm.nih.gov/pubmed/30637731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.28146
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares