Somatic genetic alterations in synchronous and metachronous low-grade serous tumours and high-grade carcinomas of the adnexa

AIMS: Low-grade serous carcinomas (LGSCs) and their precursor serous borderline tumours (SBTs) characteristically harbour mutations in BRAF, KRAS and NRAS but rarely in TP53, whereas high-grade serous carcinomas (HGSCs) are characterised by frequent TP53 mutations but rare BRAF, KRAS and NRAS mutati...

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Detalhes bibliográficos
Publicado no:Histopathology
Main Authors: Murali, Rajmohan, Selenica, Pier, Brown, David N., Cheetham, R. Keira, Chandramohan, Raghu, Claros, Nidia L., Bouvier, Nancy, Cheng, Donavan T., Soslow, Robert A., Weigelt, Britta, McCluggage, W. Glenn
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626549/
https://ncbi.nlm.nih.gov/pubmed/30565721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/his.13796
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