Molecular Characterization of High-Grade Serous Ovarian Cancers Occurring in Younger and Older Women

OBJECTIVES: To determine if the mutational landscapes and genomic features of homologous recombination DNA repair defects (HRD) vary between younger and older patients with high-grade serous ovarian cancer (HGSOC). METHODS: Younger and older women were defined as bottom and top age quartiles, respec...

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Published in:Gynecol Oncol
Main Authors: Filippova, Olga T, Selenica, Pier, Pareja, Fresia, Vahdatinia, Mahsa, Zhu, Yingjie, Pei, Xin, Riaz, Nadeem, Roche, Kara Long, Chi, Dennis S, Abu-Rustum, Nadeem R, Ellenson, Lora H, Reis-Filho, Jorge S, Zamarin, Dmitriy, Weigelt, Britta
Format: Artigo
Language:Inglês
Published: 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240481/
https://ncbi.nlm.nih.gov/pubmed/33674143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2021.02.028
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