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Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome

Our previous studies demonstrated that matrine directly acts on the replication process of porcine reproductive and respiratory syndrome virus (PRRSV). Matrine inhibits viral replication and is also associated with the NF-κB signalling pathway. These results suggest that matrine has antiviral and an...

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Detalhes bibliográficos
Publicado no:Vet Res
Main Authors: Sun, Panpan, Sun, Na, Yin, Wei, Sun, Yaogui, Fan, Kuohai, Guo, Jianhua, Khan, Ajab, He, Yongming, Li, Hongquan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626430/
https://ncbi.nlm.nih.gov/pubmed/31300043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-019-0671-x
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