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Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome

Our previous studies demonstrated that matrine directly acts on the replication process of porcine reproductive and respiratory syndrome virus (PRRSV). Matrine inhibits viral replication and is also associated with the NF-κB signalling pathway. These results suggest that matrine has antiviral and an...

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Dettagli Bibliografici
Pubblicato in:Vet Res
Autori principali: Sun, Panpan, Sun, Na, Yin, Wei, Sun, Yaogui, Fan, Kuohai, Guo, Jianhua, Khan, Ajab, He, Yongming, Li, Hongquan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626430/
https://ncbi.nlm.nih.gov/pubmed/31300043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-019-0671-x
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