AUTOPHAGY INHIBITION OVERCOMES SORAFENIB RESISTANCE IN S45F-MUTATED DESMOID TUMORS

BACKGROUND: Desmoid tumors (DTs) are rare and understudied fibroblastic lesions that are frequently recurrent and locally invasive. Desmoid tumor patients often experience chronic pain, organ dysfunction, decrease in quality of life, and even death. METHODS: Sorafenib has emerged as a promising ther...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Braggio, Danielle, Koller, David, Jin, Feng, Siva, Nanda, Zewdu, Abeba, Lopez, Gonzalo, Batte, Kara, Casadei, Lucia, Welliver, Meng, Strohecker, Anne M., Lev, Dina, Pollock, Raphael E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625904/
https://ncbi.nlm.nih.gov/pubmed/30980399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32120
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