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HIV Antibodies Decline During Antiretroviral Therapy but Remain Correlated with HIV DNA and HIV-specific T Cell Responses

BACKGROUND: In people with HIV on antiretroviral therapy (ART), the relationship between HIV-specific immune responses and measures of HIV persistence is uncertain. METHODS: We evaluated 101 individuals on suppressive ART in the AIDS Clinical Trials Group A5321 cohort. Cell-associated (CA) HIV DNA a...

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Pubblicato in:J Acquir Immune Defic Syndr
Autori principali: Keating, Sheila M., Jones, R. Brad, Lalama, Christina M., Bosch, Ronald J, McMahon, Deborah, Hampton, Dylan, Cyktor, Joshua, Eron, Joseph J., Mellors, John W., Busch, Michael P., Gandhi, Rajesh T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625873/
https://ncbi.nlm.nih.gov/pubmed/31045647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000002080
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