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Maintenance of CTCF- and transcription factor-mediated interactions from the gametes to the early mouse embryo

The epigenetic information present in mammalian gametes and whether it is transmitted to the progeny are relatively unknown. We find that many promoters in mouse sperm are occupied by RNAPII and Mediator. The same promoters are accessible in GV and MII oocytes, and preimplantation embryos. Sperm dis...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cell
Päätekijät: Jung, Yoon Hee, Kremsky, Isaac, Gold, Hannah B., Rowley, M. Jordan, Punyawai, Kanchana, Buonanotte, Alyx, Lyu, Xiaowen, Bixler, Brianna J., Chan, Anthony W. S., Corces, Victor G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625867/
https://ncbi.nlm.nih.gov/pubmed/31056445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.04.014
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