Maintenance of CTCF- and transcription factor-mediated interactions from the gametes to the early mouse embryo

The epigenetic information present in mammalian gametes and whether it is transmitted to the progeny are relatively unknown. We find that many promoters in mouse sperm are occupied by RNAPII and Mediator. The same promoters are accessible in GV and MII oocytes, and preimplantation embryos. Sperm dis...

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Publicat a:Mol Cell
Autors principals: Jung, Yoon Hee, Kremsky, Isaac, Gold, Hannah B., Rowley, M. Jordan, Punyawai, Kanchana, Buonanotte, Alyx, Lyu, Xiaowen, Bixler, Brianna J., Chan, Anthony W. S., Corces, Victor G.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625867/
https://ncbi.nlm.nih.gov/pubmed/31056445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.04.014
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