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Architectural proteins and pluripotency factors cooperate to orchestrate the transcriptional response of hESCs to temperature stress
Cells respond to temperature stress via up- and down-regulation of hundreds of genes. This process is thought to be regulated by the heat shock factor HSF1, which controls the release of RNAPII from promoter-proximal pausing. Here we analyze the events taking place in hESCs upstream of RNAPII releas...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6214669/ https://ncbi.nlm.nih.gov/pubmed/30122536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.07.012 |
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