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Architectural proteins and pluripotency factors cooperate to orchestrate the transcriptional response of hESCs to temperature stress

Cells respond to temperature stress via up- and down-regulation of hundreds of genes. This process is thought to be regulated by the heat shock factor HSF1, which controls the release of RNAPII from promoter-proximal pausing. Here we analyze the events taking place in hESCs upstream of RNAPII releas...

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Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Lyu, Xiaowen, Rowley, M. Jordan, Corces, Victor G.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214669/
https://ncbi.nlm.nih.gov/pubmed/30122536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.07.012
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