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Alternative pre-mRNA splicing switch controls hESC pluripotency and differentiation

Alternative splicing (AS) of pre-mRNAs is a ubiquitous process in mammals that is tightly regulated in a cell type- and cell state-dependent manner. However, the details of how splicing is regulated to impact specific cell fate decisions remains incompletely understood. A study by Yamazaki and colle...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Agosto, Laura M., Lynch, Kristen W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120719/
https://ncbi.nlm.nih.gov/pubmed/30181358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.318451.118
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