TCF3 alternative splicing controlled by hnRNP H/F regulates E-cadherin expression and hESC pluripotency

Alternative splicing (AS) plays important roles in embryonic stem cell (ESC) differentiation. In this study, we first identified transcripts that display specific AS patterns in pluripotent human ESCs (hESCs) relative to differentiated cells. One of these encodes T-cell factor 3 (TCF3), a transcript...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Yamazaki, Takashi, Liu, Lizhi, Lazarev, Denis, Al-Zain, Amr, Fomin, Vitalay, Yeung, Percy Luk, Chambers, Stuart M., Lu, Chi-Wei, Studer, Lorenz, Manley, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120717/
https://ncbi.nlm.nih.gov/pubmed/30115631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.316984.118
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