TCF3 alternative splicing controlled by hnRNP H/F regulates E-cadherin expression and hESC pluripotency

Alternative splicing (AS) plays important roles in embryonic stem cell (ESC) differentiation. In this study, we first identified transcripts that display specific AS patterns in pluripotent human ESCs (hESCs) relative to differentiated cells. One of these encodes T-cell factor 3 (TCF3), a transcript...

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Enregistré dans:
Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Yamazaki, Takashi, Liu, Lizhi, Lazarev, Denis, Al-Zain, Amr, Fomin, Vitalay, Yeung, Percy Luk, Chambers, Stuart M., Lu, Chi-Wei, Studer, Lorenz, Manley, James L.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2018
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120717/
https://ncbi.nlm.nih.gov/pubmed/30115631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.316984.118
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