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Unexpected implications of STAT3 acetylation revealed by genetic encoding of acetyl-lysine

The signal transducer and activator of transcription 3 (STAT3) protein is activated by phosphorylation of a specific tyrosine residue (Tyr705) in response to various extracellular signals. STAT3 activity was also found to be regulated by acetylation of Lys685. However, the molecular mechanism by whi...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Gen Subj
Main Authors: Belo, Yael, Mielko, Zachery, Nudelman, Hila, Afek, Ariel, Ben-David, Oshrit, Shahar, Anat, Zarivach, Raz, Gordan, Raluca, Arbely, Eyal
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625855/
https://ncbi.nlm.nih.gov/pubmed/31170499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2019.05.019
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