Calcium-sensing receptor promotes high glucose-induced myocardial fibrosis via upregulation of the TGF-β(1)/Smads pathway in cardiac fibroblasts

Diabetic cardiomyopathy (DCM) is a major complication of diabetes and myocardial fibrosis is its major pathological feature. Calcium-sensing receptor (CaSR) is a G protein-coupled receptor and participates in the regulation of calcium homeostasis; it is implicated in a range of diseases, including m...

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Publicat a:Mol Med Rep
Autors principals: Yuan, Hui, Fan, Yuqi, Wang, Yuehong, Gao, Tielei, Shao, Yiying, Zhao, Bingbing, Li, Hongzhu, Xu, Changqing, Wei, Can
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625450/
https://ncbi.nlm.nih.gov/pubmed/31173208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10330
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