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TET2 missense variants in human neoplasia. A proposal of structural and functional classification
BACKGROUND: The human TET2 gene plays a pivotal role in the epigenetic regulation of normal and malignant hematopoiesis. Somatic TET2 mutations have been repeatedly identified in age‐related clonal hematopoiesis and in myeloid neoplasms ranging from acute myeloid leukemia (AML) to myeloproliferative...
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| 出版年: | Mol Genet Genomic Med |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6625141/ https://ncbi.nlm.nih.gov/pubmed/31187595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.772 |
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