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TET2 missense variants in human neoplasia. A proposal of structural and functional classification
BACKGROUND: The human TET2 gene plays a pivotal role in the epigenetic regulation of normal and malignant hematopoiesis. Somatic TET2 mutations have been repeatedly identified in age‐related clonal hematopoiesis and in myeloid neoplasms ranging from acute myeloid leukemia (AML) to myeloproliferative...
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| Publicat a: | Mol Genet Genomic Med |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6625141/ https://ncbi.nlm.nih.gov/pubmed/31187595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.772 |
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