A novel model of controlling PD-L1 expression in ALK(+) anaplastic large cell lymphoma revealed by CRISPR screening

The success of programmed cell death protein 1 (PD-1)/PD-L1-based immunotherapy highlights the critical role played by PD-L1 in cancer progression and reveals an urgent need to develop new approaches to attenuate PD-L1 function by gaining insight into how its expression is controlled. Anaplastic lym...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Zhang, Jing-Ping, Song, Zhihui, Wang, Hong-Bo, Lang, Lang, Yang, Yuan-Zhong, Xiao, Wenming, Webster, Daniel E., Wei, Wei, Barta, Stefan K., Kadin, Marshall E., Staudt, Louis M., Nakagawa, Masao, Yang, Yibin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624970/
https://ncbi.nlm.nih.gov/pubmed/31151983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019001043
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