Cytokine receptor signaling is required for the survival of ALK− anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations

Activating Janus kinase (JAK) and signal transducer and activator of transcription (STAT) mutations have been discovered in many T-cell malignancies, including anaplastic lymphoma kinase (ALK)(−) anaplastic large cell lymphomas (ALCLs). However, such mutations occur in a minority of patients. To inv...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Jing, Zhang, Yong, Petrus, Michael N., Xiao, Wenming, Nicolae, Alina, Raffeld, Mark, Pittaluga, Stefania, Bamford, Richard N., Nakagawa, Masao, Ouyang, Sunny Tianyi, Epstein, Alan L., Kadin, Marshall E., Del Mistro, Annarose, Woessner, Richard, Jaffe, Elaine S., Waldmann, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393253/
https://ncbi.nlm.nih.gov/pubmed/28356514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700682114
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