Reprogramming identifies functionally distinct stages of clonal evolution in myelodysplastic syndromes

Myeloid neoplasms, including myelodysplastic syndromes (MDS), are genetically heterogeneous disorders driven by clonal acquisition of somatic mutations in hematopoietic stem and progenitor cells (HPCs). The order of premalignant mutations and their impact on HPC self-renewal and differentiation rema...

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發表在:Blood
Main Authors: Hsu, Jasper, Reilly, Andreea, Hayes, Brian J., Clough, Courtnee A., Konnick, Eric Q., Torok-Storb, Beverly, Gulsuner, Suleyman, Wu, David, Becker, Pamela S., Keel, Siobán B., Abkowitz, Janis L., Doulatov, Sergei
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2019
主題:
Myeloid Neoplasia
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624967/
https://ncbi.nlm.nih.gov/pubmed/31010849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2018884338
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