Reprogramming identifies functionally distinct stages of clonal evolution in myelodysplastic syndromes

Myeloid neoplasms, including myelodysplastic syndromes (MDS), are genetically heterogeneous disorders driven by clonal acquisition of somatic mutations in hematopoietic stem and progenitor cells (HPCs). The order of premalignant mutations and their impact on HPC self-renewal and differentiation rema...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Hsu, Jasper, Reilly, Andreea, Hayes, Brian J., Clough, Courtnee A., Konnick, Eric Q., Torok-Storb, Beverly, Gulsuner, Suleyman, Wu, David, Becker, Pamela S., Keel, Siobán B., Abkowitz, Janis L., Doulatov, Sergei
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2019
Matèries:
Myeloid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624967/
https://ncbi.nlm.nih.gov/pubmed/31010849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2018884338
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