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RESCUE: imputing dropout events in single-cell RNA-sequencing data

BACKGROUND: Single-cell RNA-sequencing technologies provide a powerful tool for systematic dissection of cellular heterogeneity. However, the prevalence of dropout events imposes complications during data analysis and, despite numerous efforts from the community, this challenge has yet to be solved....

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Publicat a:BMC Bioinformatics
Autors principals: Tracy, Sam, Yuan, Guo-Cheng, Dries, Ruben
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624880/
https://ncbi.nlm.nih.gov/pubmed/31299886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2977-0
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