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RESCUE: imputing dropout events in single-cell RNA-sequencing data

BACKGROUND: Single-cell RNA-sequencing technologies provide a powerful tool for systematic dissection of cellular heterogeneity. However, the prevalence of dropout events imposes complications during data analysis and, despite numerous efforts from the community, this challenge has yet to be solved....

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Tracy, Sam, Yuan, Guo-Cheng, Dries, Ruben
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624880/
https://ncbi.nlm.nih.gov/pubmed/31299886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2977-0
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