Comparison of pharmacokinetics and the exposure–response relationship of dapagliflozin between adolescent/young adult and adult patients with type 1 diabetes mellitus

AIMS: To quantitatively compare pharmacokinetics (PK) and the exposure–response (ER) relationship of the sodium‐glucose cotransporter‐2 inhibitor, dapagliflozin, between adolescents/young adults and adults with type 1 diabetes mellitus (T1DM). METHODS: Data from 2 clinical studies for dapagliflozin...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Busse, David, Tang, Weifeng, Scheerer, Markus, Danne, Thomas, Biester, Torben, Sokolov, Viktor, Boulton, David, Parkinson, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624399/
https://ncbi.nlm.nih.gov/pubmed/31077437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13981
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