Model‐based characterization of the relationship between dapagliflozin systemic exposure and HbA1c response in patients with type 1 diabetes mellitus

AIMS: To quantitatively describe the relationship between dapagliflozin systemic exposure and HbA1c response among patients with type 1 diabetes mellitus (T1DM) and assess the potential impact of covariate effects. MATERIALS AND METHODS: Individual longitudinal HbA1c data from two phase 3 studies in...

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Detalhes bibliográficos
Publicado no:Diabetes Obes Metab
Main Authors: Parkinson, Joanna, Tang, Weifeng, Åstrand, Magnus, Melin, Johanna, Ekholm, Ella, Hamrén, Bengt, Boulton, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594233/
https://ncbi.nlm.nih.gov/pubmed/30756462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13664
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