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Population pharmacokinetic model and Bayesian estimator for 2 tacrolimus formulations in adult liver transplant patients

AIMS: Tacrolimus is a narrow therapeutic range drug that requires fine dose adjustment, for which pharmacokinetic (PK) models have been amply proposed in renal, but not in liver, transplant recipients. This study aimed to build population PK models and Bayesian estimators (BEs) in adult de novo live...

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Bibliografiske detaljer
Udgivet i:Br J Clin Pharmacol
Main Authors: Riff, Camille, Debord, Jean, Monchaud, Caroline, Marquet, Pierre, Woillard, Jean‐Baptiste
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624397/
https://ncbi.nlm.nih.gov/pubmed/30973981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13960
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