A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression

Adolescent idiopathic scoliosis is the most prevalent spine deformity and the molecular mechanisms underlying its pathophysiology remain poorly understood. We have previously found a differential impairment of melatonin receptor signaling in AIS osteoblasts allowing the classification of patients in...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Akoume, Marie-Yvonne, Elbakry, Mohamed, Veillette, Maxime, Franco, Anita, Nada, Dina, Labelle, Hubert, Mac-Thiong, Jean-Marc, Grimard, Guy, Ouellet, Jean, Parent, Stefan, Rivard, Charles-Hilaire, Lombardi, Giovanni, Colombini, Alessandra, Banfi, Giuseppe, Brayda-Bruno, Marco, Gorman, Kristen F., Moreau, Alain
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624302/
https://ncbi.nlm.nih.gov/pubmed/31296888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46325-2
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