A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression

Adolescent idiopathic scoliosis is the most prevalent spine deformity and the molecular mechanisms underlying its pathophysiology remain poorly understood. We have previously found a differential impairment of melatonin receptor signaling in AIS osteoblasts allowing the classification of patients in...

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Vydáno v:Sci Rep
Hlavní autoři: Akoume, Marie-Yvonne, Elbakry, Mohamed, Veillette, Maxime, Franco, Anita, Nada, Dina, Labelle, Hubert, Mac-Thiong, Jean-Marc, Grimard, Guy, Ouellet, Jean, Parent, Stefan, Rivard, Charles-Hilaire, Lombardi, Giovanni, Colombini, Alessandra, Banfi, Giuseppe, Brayda-Bruno, Marco, Gorman, Kristen F., Moreau, Alain
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624302/
https://ncbi.nlm.nih.gov/pubmed/31296888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46325-2
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