A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression

Adolescent idiopathic scoliosis is the most prevalent spine deformity and the molecular mechanisms underlying its pathophysiology remain poorly understood. We have previously found a differential impairment of melatonin receptor signaling in AIS osteoblasts allowing the classification of patients in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Akoume, Marie-Yvonne, Elbakry, Mohamed, Veillette, Maxime, Franco, Anita, Nada, Dina, Labelle, Hubert, Mac-Thiong, Jean-Marc, Grimard, Guy, Ouellet, Jean, Parent, Stefan, Rivard, Charles-Hilaire, Lombardi, Giovanni, Colombini, Alessandra, Banfi, Giuseppe, Brayda-Bruno, Marco, Gorman, Kristen F., Moreau, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624302/
https://ncbi.nlm.nih.gov/pubmed/31296888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46325-2
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