The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial

BACKGROUND: Safe and effective vaccines against Ebola could prevent or control outbreaks. The safe use of replication-competent vaccines requires a careful dose-selection process. We report the first safety and immunogenicity results in volunteers receiving 3 × 10(5) plaque-forming units (pfu) of th...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Lancet Infect Dis
Hlavní autoři: Huttner, Angela, Dayer, Julie-Anne, Yerly, Sabine, Combescure, Christophe, Auderset, Floriane, Desmeules, Jules, Eickmann, Markus, Finckh, Axel, Goncalves, Ana Rita, Hooper, Jay W, Kaya, Gürkan, Krähling, Verena, Kwilas, Steve, Lemaître, Barbara, Matthey, Alain, Silvera, Peter, Becker, Stephan, Fast, Patricia E, Moorthy, Vasee, Kieny, Marie Paule, Kaiser, Laurent, Siegrist, Claire-Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624136/
https://ncbi.nlm.nih.gov/pubmed/26248510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(15)00154-1
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky