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Role of the Glyoxalase System in Astrocyte-Mediated Neuroprotection

The glyoxalase system is the most important pathway for the detoxification of methylglyoxal (MG), a highly reactive dicarbonyl compound mainly formed as a by-product of glycolysis. MG is a major precursor of advanced glycation end products (AGEs), which are associated with several neurodegenerative...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Bélanger, Mireille, Yang, Jiangyan, Petit, Jean-Marie, Laroche, Thierry, Magistretti, Pierre J., Allaman, Igor
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623908/
https://ncbi.nlm.nih.gov/pubmed/22171037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1249-11.2011
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