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Amyloid-β Aggregates Cause Alterations of Astrocytic Metabolic Phenotype: Impact on Neuronal Viability

Amyloid-β (Aβ) peptides play a key role in the pathogenesis of Alzheimer's disease and exert various toxic effects on neurons; however, relatively little is known about their influence on glial cells. Astrocytes play a pivotal role in brain homeostasis, contributing to the regulation of local e...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Allaman, Igor, Gavillet, Mathilde, Bélanger, Mireille, Laroche, Thierry, Viertl, David, Lashuel, Hilal A., Magistretti, Pierre J.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6634099/
https://ncbi.nlm.nih.gov/pubmed/20203192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5098-09.2010
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