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Multiple Targets of μ-Opioid Receptor-Mediated Presynaptic Inhibition at Primary Afferent Aδ- and C-Fibers

Agonists at μ-opioid receptors (MORs) represent the gold standard for the treatment of severe pain. A key element of opioid analgesia is the depression of nociceptive information at the first synaptic relay in spinal pain pathways. The underlying mechanisms are, however, largely unknown. In spinal c...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Heinke, Bernhard, Gingl, Ewald, Sandkühler, Jürgen
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623607/
https://ncbi.nlm.nih.gov/pubmed/21273416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4060-10.2011
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