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Presynaptic inhibition of optogenetically identified VGluT3(+) sensory fibres by opioids and baclofen

Distinct subsets of sensory nerve fibres are involved in mediating mechanical and thermal pain hypersensitivity. They may also differentially respond to analgesics. Heat-sensitive C-fibres, for example, are thought to respond to µ-opioid receptor (MOR) activation while mechanoreceptive fibres are su...

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Publicado en:Pain
Autores principales: Honsek, Silke D., Seal, Rebecca P., Sandkühler, Jürgen
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299913/
https://ncbi.nlm.nih.gov/pubmed/25599445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.j.pain.0000460304.63948.40
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