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Long-Term In Vivo Imaging of β-Amyloid Plaque Appearance and Growth in a Mouse Model of Cerebral β-Amyloidosis

Extracellular deposition of the amyloid-β peptide (Aβ) in the brain parenchyma is a hallmark lesion of Alzheimer's disease (AD) and a predictive marker for the progression of preclinical to symptomatic AD. Here, we used multiphoton in vivo imaging to study Aβ plaque formation in the brains of 3...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Hefendehl, Jasmin K., Wegenast-Braun, Bettina M., Liebig, Christian, Eicke, Daniel, Milford, David, Calhoun, Michael E., Kohsaka, Shinichi, Eichner, Martin, Jucker, Mathias
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623424/
https://ncbi.nlm.nih.gov/pubmed/21228171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5147-10.2011
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